USMLE-Rx Step 1 Qmax Challenge #4101

Check out today’s Step 1 Qmax Question Challenge.

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A 19-year-old college student presents for evaluation of persistently enlarged nontender supraclavicular lymph nodes. She says she is otherwise healthy and provides no significant medical history. She is experiencing night sweats and has had a 4.5-kg (10-lb) weight loss over the past 3 months. Three supraclavicular lymph nodes are palpable above her right shoulder. No other lymphadenopathy is noted. On X-ray of the chest, mediastinal lymphadenopathy is noted. Results of a lymph node biopsy are shown in the image.

Which of the following is the most likely diagnosis?

A. Burkitt lymphoma
B. Follicular lymphoma
C. Hodgkin lymphoma, lymphocyte-depleted type
D. Hodgkin lymphoma, nodular-sclerosing type
E. T-lymphocyte lymphoblastic lymphoma

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