A 2-year-old girl is brought to the clinic by her adoptive parents for a well-child examination. The patient’s parents do not know the detailed medical history of her biological parents. Her height is below the second percentile, and her weight is below the third percentile. On examination, the patient appears to have a normal trunk size, but her head appears large and her arms and legs appear short. The remainder of the examination findings are within normal limits.
Which of the following is associated with this condition?
A. Advanced maternal age
B. Advanced paternal age
C. Growth hormone deficiency
D. Iodine deficiency in utero
E. Thalidomide exposure in utero
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