Step 1 Question of the Week – 10/12/20

This week’s USMLE Step 1 question comes from the area of respiratory physiology.  See if you can answer the question and then watch the video to learn the correct answer as well as the rationales for all of the options.  The video comes from a recent edition of the Rx Question Lab, so if you like it, we encourage you to register and tune in every Tuesday.


A 67-year-old man comes to the local community health care clinic and reports shortness of breath after even brief exertion and a chronic nonproductive cough. He is a retired construction worker and has a 40-pack-year history of cigarette smoking. He is allergic to penicillin. A chest x-ray reveals scattered calcifications in the peripheral lymph nodes of the upper lobes. The pulmonary function test result is shown in the image.


Which of the following is the most likely diagnosis?

A. Asbestosis
B. Berylliosis
C. Chronic obstructive pulmonary disease
D. Coal workers’ pneumoconiosis
E. Silicosis

We invite you to leave a comment with your answer as well as your rationale.  When you’re ready to check your work, watch the video.

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