This week’s edition of the Step 1 Question of the Week is about immunology. See if you can answer the question and then watch the video to learn the correct answer as well as the rationales for each option.
A 16-year-old boy comes to the physician’s office because he is concerned about seeing blood in his urine for the past 3 days. The patient reports painless urination and mild lower back pain. He has also had a sore throat with white tonsillar patches ever since the urinary changes occurred. He reports having a upper respiratory infection over the past 5 days. His temperature is 36°C, blood pressure is 134/85 mm Hg, and pulse is 89/min. Laboratory studies show normal serum blood urea nitrogen and creatinine, red blood cell casts in the urine, and proteinuria of 2.5 g/day. Complement levels are normal. No masses are detected on ultrasound on the abdomen.
Which of the following is most likely to be found on microscopic evaluation of a renal biopsy?
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